Continuous Positive Airway Pressure (CPAP) Therapy for ...

British Columbia Specific Information

Positive airway pressure (PAP) therapy is a generic term applied to therapy devices that treat obstructive sleep apnea (OSA) by using a stream of compressed air to support the upper airway during sleep. PAP therapy should only be prescribed by a referring practitioner (physician or nurse practitioner) or specialist after a patient has undergone a physical evaluation and appropriate diagnostic testing.

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The Positive Airway Pressure Buyer's Guide was created by the Ministry of Health to support patients when purchasing a Positive Airway Pressure device. It includes information on:

• Machine and mask types
• Machine options and features
• Funding options
• Provider details, including location and contact information

The Buyer's Guide does not endorse any particular therapy and is not a substitute for expert clinic advice. Rather, it is intended to augment current informational materials that may be provided to patients and referring practitioners.

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1 Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2 Umraniye Education and Research Hospital, Istanbul, Turkey

Introduction: The number and morphology of telangiectases (T) have been studied in terms of severity and organ involvement in systemic sclerosis (SSc). T are located more frequently on face and trunk than extremities. We aimed to evaluate the impact of the localization of T on different skin areas in addition to number, on disease severity of SSc.

Material and Methods: SSc patients fulfilling ACR/EULAR classification criteria () who had the manifestation T were included. The number of T were calculated by using telangiectasia score (TS)(Shah A.,et al) and localization was classified according to presence of T on extremities or not. Simultaneously; ealy, active and late scleroderma patterns (Cutolo et al.) were determined qualitatively and capillary number (CN) was calculated per linear mm at distal row quantitatively by using nail fold video-capillaroscopy (NVC) in all patients.

Results: In 113 (106 female) SSc patients with T; the mean age was 52±12, the duration of follow-up 57±62 months, Raynaud and non-Raynaud symptom 10±8 and 7±7 years. Limited cutaneous form was found to be in 77 (%68), ANA positivity in 102 (%90) ve anti-Scl70 positivity in 33 (%29) patients. In SSc patients with TS score more than 6 or extremity T; the duration of non-Raynaud symptom was found to be longer (p=0,010 or 0,009), MRSS and activity scores were higher (p=0,004 or 0,012 and p=0,010 or 0,009) and severity scores of general, peripheral vascular involvement and skin were higher (p=0,022 or 0,014, p=0,030 or 0,025 and p=0,006 or 0,02), digital ulcers and flexion contractures were more frequent (p=0,008 or 0,035 and p=0,027 or 0,032), late NVC pattern was more frequent and CN was lower (p=0,001 or 0,003 and p=0,001 or 0,007).

When patients were classified in 3 groups according to TS and presence of extremity T, differences in terms of organ involvement, disease activity and severity scores and NVC findings were summarized in table-1.

Conclusions: Conclusion: Disease duration was shown to be long, disease activity and severity were high and NVC findings were severe in patients with high scores of TS and extremity T. In patients with lower TS the presence of T on extremities was found to be related to severe disease. The number and localization of T was emphasized as they are easy to evaluate in clinical practice and may be useful in determining severe patients with SSc.

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